| Jumping Gully | Kershaw, SC | 7.9 miles | SW |
| Gilles Ditch | Kershaw, SC | 8.5 miles | SW |
| Wateree Canal (historical) | Kershaw, SC | 9 miles | NW |
| Atkins Drainage Canal | Lee, SC | 29.5 miles | SE |
| Jeffries Ditch | Darlington, SC | 30.9 miles | NE |
| Main Line Ditch | Richland, SC | 32.3 miles | SW |
| Columbia Canal | Richland, SC | 32.4 miles | SW |
| Landsford Canal | Chester, SC | 38.3 miles | NW |
| Polk Swamp Canal | Florence, SC | 53.4 miles | SE |
| Kingstree Swamp Canal | Williamsburg, SC | 54.1 miles | SE |
| High Hill Drainage Canal | Florence, SC | 55.8 miles | SE |
| Lockharts Canala | Union, SC | 60.8 miles | NW |
| Polk Ditch | Mecklenburg, NC | 61.1 miles | NW |
| Santee Canal | Berkeley, SC | 65.2 miles | SE |
| Bulltown Ditch | Berkeley, SC | 66.8 miles | SE |
| Catfish Canal | Marion, SC | 67.6 miles | SE |
| Isaac Jennings Canal | Orangeburg, SC | 68.3 miles | SW |
| Fox Swamp Canal | Dillon, SC | 70.6 miles | NE |
| Ophir Canal (historical) | Berkeley, SC | 73.8 miles | SE |
| Moultrie Canal (historical) | Berkeley, SC | 75.3 miles | SE |
| Tailrace Canal | Berkeley, SC | 81 miles | SE |
| Old Santee Canal | Berkeley, SC | 81.3 miles | SE |
| The Canal | Stanly, NC | 85.6 miles | NE |
| Boyd Canal | Horry, SC | 87.3 miles | SE |
| Gum Branch Canal | Robeson, NC | 92 miles | NE |
| Stevens Canal | Robeson, NC | 93.6 miles | NE |
| Big Branch Canal | Robeson, NC | 94 miles | NE |
| Hester Canal | Berkeley, SC | 94.4 miles | SE |
| Piney Island Canal | Robeson, NC | 95 miles | NE |
| Willoughby Canal | Robeson, NC | 96.2 miles | NE |
| Gum Swamp Canal | Robeson, NC | 97.1 miles | NE |
| Augusta Canal | Richmond, GA | 97.1 miles | SW |
| Big Swamp Canal | Robeson, NC | 97.2 miles | NE |
| Beaverdam Ditch | Richmond, GA | 98.6 miles | SW |
| Phinizy Ditch | Richmond, GA | 99.4 miles | SW |
| Sevenmile Viaduct | Charleston, SC | 103 miles | SE |
| Estherville Minim Creek Canal | Georgetown, SC | 105.1 miles | SE |
| Fivemile Viaduct | Charleston, SC | 105.3 miles | SE |
| Fourmile Creek Canal | Georgetown, SC | 106.5 miles | SE |
| Rockfish Canal | Georgetown, SC | 107.7 miles | SE |
| Mosquito Creek Canal | Georgetown, SC | 108.8 miles | SE |
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