| Isaac Jennings Canal | Orangeburg, SC | 11.1 miles | NW |
| Bulltown Ditch | Berkeley, SC | 42.1 miles | NE |
| Ophir Canal (historical) | Berkeley, SC | 42.1 miles | NE |
| Santee Canal | Berkeley, SC | 43 miles | NE |
| Moultrie Canal (historical) | Berkeley, SC | 45.2 miles | NE |
| Matthews Canal | Colleton, SC | 48.4 miles | SE |
| Old Santee Canal | Berkeley, SC | 48.5 miles | SE |
| Tailrace Canal | Berkeley, SC | 48.6 miles | SE |
| Sevenmile Viaduct | Charleston, SC | 54.3 miles | SE |
| Columbia Canal | Richland, SC | 54.9 miles | NW |
| Fivemile Viaduct | Charleston, SC | 56.7 miles | SE |
| Main Line Ditch | Richland, SC | 58 miles | NW |
| Switzerland Canal | Jasper, SC | 58.1 miles | SW |
| Hester Canal | Berkeley, SC | 60.2 miles | SE |
| Gilles Ditch | Kershaw, SC | 64.3 miles | NE |
| Jumping Gully | Kershaw, SC | 64.4 miles | NE |
| Beaverdam Ditch | Richmond, GA | 67.4 miles | NW |
| Phinizy Ditch | Richmond, GA | 67.7 miles | NW |
| Atkins Drainage Canal | Lee, SC | 68.7 miles | NE |
| Kingstree Swamp Canal | Williamsburg, SC | 69.2 miles | NE |
| Augusta Canal | Richmond, GA | 70.4 miles | NW |
| Lucknow Canal | Jasper, SC | 75.9 miles | SW |
| Wateree Canal (historical) | Kershaw, SC | 76.4 miles | NE |
| Taylor Canal | Jasper, SC | 76.8 miles | SW |
| High Hill Drainage Canal | Florence, SC | 78.9 miles | NE |
| Murray Hill Canal | Jasper, SC | 79.1 miles | SW |
| Shubra Canal | Jasper, SC | 80 miles | SW |
| Clydesdale Canal | Jasper, SC | 80 miles | SW |
| Pipe Makers Canal | Chatham, GA | 81.5 miles | SW |
| Springfield Canal | Chatham, GA | 83.2 miles | SW |
| Hardin Canal | Chatham, GA | 83.8 miles | SW |
| Savannah and Ogeechee Canal | Chatham, GA | 84 miles | SW |
| Placentia Canal | Chatham, GA | 84.9 miles | SW |
| Jeffries Ditch | Darlington, SC | 85.1 miles | NE |
| Fourmile Creek Canal | Georgetown, SC | 87.2 miles | SE |
| Estherville Minim Creek Canal | Georgetown, SC | 89.4 miles | SE |
| Polk Swamp Canal | Florence, SC | 91.7 miles | NE |
| Rockfish Canal | Georgetown, SC | 92.3 miles | SE |
| Mosquito Creek Canal | Georgetown, SC | 92.9 miles | SE |
| Peachtree Canal | Chatham, GA | 93.8 miles | SW |
| Valambrosia Canal | Chatham, GA | 93.8 miles | SW |
| Southfield Canal | Chatham, GA | 94 miles | SW |
| Walker Canal | Chatham, GA | 94.3 miles | SW |
| New Hope Canal | Chatham, GA | 94.9 miles | SW |
| Five Docks Canal | Chatham, GA | 94.9 miles | SW |
| Elbow Canal | Chatham, GA | 95 miles | SW |
| Red Dock Canal | Chatham, GA | 95 miles | SW |
| Catfish Canal | Marion, SC | 103.1 miles | NE |
| Boyd Canal | Horry, SC | 103.8 miles | NE |
| Fox Swamp Canal | Dillon, SC | 115 miles | NE |
|