| Orangeburg Municipal Airport | Orangeburg, SC | 12.5 miles | NW |
| Russell Airport | Orangeburg, SC | 13.2 miles | NE |
| McNeil Airport | Calhoun, SC | 14.5 miles | NE |
| Saint George Municipal Airport | Dorchester, SC | 14.9 miles | SE |
| Regional Medical Center of Orangeburg and Calhoun County Heliport | Orangeburg, SC | 15.5 miles | NW |
| Santee Golf Air Strip | Orangeburg, SC | 16.3 miles | NE |
| Holly Hill Airport | Orangeburg, SC | 17.3 miles | SE |
| Bamberg Hospital Heliport | Bamberg, SC | 19.8 miles | SW |
| Saint Matthews Airport | Calhoun, SC | 23.3 miles | NW |
| Bamberg County Airport | Bamberg, SC | 24.6 miles | SW |
| Crosswinds-Wilson Private Airport | Berkeley, SC | 25.6 miles | SE |
| Ehrhardt Airport | Bamberg, SC | 25.8 miles | SW |
| Alans Airport | Calhoun, SC | 27 miles | NW |
| North Air Force Auxiliary Field | Orangeburg, SC | 29.4 miles | NW |
| Walterboro Municipal Airport | Colleton, SC | 29.8 miles | SE |
| Dorchester County Airport | Dorchester, SC | 30.8 miles | SE |
| Broxton Bridge Plantation Airport | Colleton, SC | 31.6 miles | SW |
| Santee Cooper Regional Airport | Clarendon, SC | 32.2 miles | NE |
| Clarendon Memorial Hospital Heliport | Clarendon, SC | 36.1 miles | NE |
| Lexington County Airport | Lexington, SC | 38.3 miles | NW |
| Phillips Airstrip | Allendale, SC | 38.3 miles | SW |
| Creech Aviation Facility Airport | Sumter, SC | 38.7 miles | NE |
| Monoghan Auxiliary Airfield (historical) | Sumter, SC | 39.3 miles | NE |
| Berkeley County Airport | Berkeley, SC | 39.3 miles | SE |
| Hampton-Varnville Airport | Hampton, SC | 40.4 miles | SW |
| Barnwell County Airport | Barnwell, SC | 41 miles | SW |
| Sugar Hill Airport | Allendale, SC | 41.1 miles | SW |
| Hampton General Hospital Heliport | Hampton, SC | 41.5 miles | SW |
| Allendale County Airport | Allendale, SC | 41.7 miles | SW |
| Darden Airport | Lexington, SC | 44.4 miles | NW |
| Corporate Airport | Lexington, SC | 44.5 miles | NW |
| Oswald Field | Allendale, SC | 45.3 miles | SW |
| Falcon Airport | Lexington, SC | 45.8 miles | NW |
| Columbia Owens Downtown Airport | Richland, SC | 46.5 miles | NW |
| Owens Field Airport | Richland, SC | 46.8 miles | NW |
| Lane Airport (historical) | Williamsburg, SC | 47.1 miles | NE |
| Columbia Metropolitan Airport | Lexington, SC | 47.9 miles | NW |
| Eagles Nest-Fairview Airpark | Lexington, SC | 48.2 miles | NW |
| Sumter Municipal Airport | Sumter, SC | 48.5 miles | NE |
| Charleston International Airport | Charleston, SC | 48.7 miles | SE |
| Palmetto Center Heliport | Richland, SC | 49.5 miles | NW |
| Providence Hospital Heliport | Richland, SC | 49.7 miles | NW |
| Dabbs Airport | Sumter, SC | 50 miles | NE |
| Airy Hall Airport | Colleton, SC | 50.7 miles | SE |
| Richland Memorial Hospital Heliport | Richland, SC | 51 miles | NW |
| Lexington Medical Center Heliport | Lexington, SC | 51 miles | NW |
| Too Goo Doo Farms Airport | Charleston, SC | 51.2 miles | SE |
| Harpers Airport | Hampton, SC | 51.4 miles | SW |
| Yonges Island Airport | Charleston, SC | 52.4 miles | SE |
| Byrd Field | Clarendon, SC | 54.2 miles | NE |
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