| Berkeley County Airport | Berkeley, SC | 9.6 miles | SW |
| Lane Airport (historical) | Williamsburg, SC | 12.7 miles | NE |
| Crosswinds-Wilson Private Airport | Berkeley, SC | 15.7 miles | SW |
| Santee Cooper Regional Airport | Clarendon, SC | 22.5 miles | NW |
| Holly Hill Airport | Orangeburg, SC | 23.5 miles | SW |
| Dorchester County Airport | Dorchester, SC | 24.4 miles | SW |
| Russell Airport | Orangeburg, SC | 27.4 miles | NW |
| Andrews Municipal Airport | Georgetown, SC | 28.2 miles | NE |
| Clarendon Memorial Hospital Heliport | Clarendon, SC | 28.5 miles | NW |
| Williamsburg County Airport | Williamsburg, SC | 28.6 miles | NE |
| Charleston International Airport | Charleston, SC | 29.2 miles | SW |
| Santee Golf Air Strip | Orangeburg, SC | 29.4 miles | NW |
| Saint George Municipal Airport | Dorchester, SC | 31.3 miles | SW |
| East Cooper Airport | Charleston, SC | 31.4 miles | SE |
| Ravens Run Airport | Charleston, SC | 35.8 miles | SE |
| Medical University of South Carolina Heliport | Charleston, SC | 36.8 miles | SE |
| Georgetown County Airport | Georgetown, SC | 38.8 miles | SE |
| Byrd Field | Clarendon, SC | 39.1 miles | NW |
| Lake City Municipal Airport | Florence, SC | 39.2 miles | NE |
| Hemingway-Stuckey Airport | Williamsburg, SC | 39.3 miles | NE |
| McNeil Airport | Calhoun, SC | 41.5 miles | NW |
| Dabbs Airport | Sumter, SC | 41.9 miles | NW |
| Charleston Executive Airport | Charleston, SC | 42.7 miles | SW |
| Monoghan Auxiliary Airfield (historical) | Sumter, SC | 43.6 miles | NW |
| Cockfield Aerodrome | Florence, SC | 44.1 miles | NE |
| Yonges Island Airport | Charleston, SC | 45.1 miles | SW |
| Too Goo Doo Farms Airport | Charleston, SC | 45.2 miles | SW |
| Walterboro Municipal Airport | Colleton, SC | 46.8 miles | SW |
| Saint Matthews Airport | Calhoun, SC | 47.8 miles | NW |
| W B Upshur Private Airport | Charleston, SC | 47.9 miles | SW |
| Creech Aviation Facility Airport | Sumter, SC | 48.8 miles | NW |
| Regional Medical Center of Orangeburg and Calhoun County Heliport | Orangeburg, SC | 51 miles | NW |
| Orangeburg Municipal Airport | Orangeburg, SC | 51.2 miles | NW |
| Sumter Municipal Airport | Sumter, SC | 51.5 miles | NW |
| Tallon Field | Lee, SC | 54.7 miles | NW |
| McKay Airport | Florence, SC | 55 miles | NE |
| Airy Hall Airport | Colleton, SC | 56.1 miles | SW |
| Huggins Memorial Airport | Florence, SC | 56.8 miles | NE |
| Lamar Airport | Darlington, SC | 59 miles | NW |
| Bamberg Hospital Heliport | Bamberg, SC | 60.1 miles | SW |
| Alans Airport | Calhoun, SC | 60.5 miles | NW |
| Conway-Horry County Airport | Horry, SC | 61.1 miles | NE |
| Ehrhardt Airport | Bamberg, SC | 61.1 miles | SW |
| Florence Regional Airport | Florence, SC | 61.8 miles | NE |
| Javika Airport | Horry, SC | 61.8 miles | NE |
| El Porvenir Airpark | Kershaw, SC | 64.6 miles | NW |
| Bamberg County Airport | Bamberg, SC | 64.8 miles | SW |
| Broxton Bridge Plantation Airport | Colleton, SC | 65.1 miles | SW |
| Lee County Airport | Lee, SC | 65.6 miles | NW |
| Myrtle Beach International Airport | Horry, SC | 66.1 miles | NE |
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